The rapid, chemically-specific detection of aerosols is of great interest to atmospheric chemistry research due to aerosol human health hazards and their effects on climate forcing. Functional group analysis of aerosols is commonly done by collecting particles on a filter over time, then extracting and analyzing the sample using Fourier Transform Infrared spectroscopy (FTIR). However, this method typically limits temporal resolution to timescales of hours/days. A method for real-time, standoff functional group analysis of aerosols was developed using mid-infrared dual comb spectroscopy (DCS). A novel galvanized steel aerosol chamber, including aerosol generation and physical and chemical characterization, was developed for testing this technology. Aerosols of multiple pure species were generated in this chamber on a background of common atmospheric gases, and were detected by DCS. Ongoing work is being done to detect chemical changes in the aerosol phase. The reaction between oleic acid aerosols and nitrate radicals has been generated and characterized with traditional instrumentation. If the organic nitrate products of this reaction can be detected with high time resolution, then DCS will be useful for elucidating many other aerosol-phase reactions in real time.